| 2019 |
Lee YJ, Chang GD*. (2019) Quantitative display of the redox status of proteins with maleimide-polyethylene glycol tagging. In press. |
| Lee CY, Su GC, Huang WY, Ko MY, Yeh HY, Chang GD, Lin SJ, Chi P. (2019) Promotion of homology-directed DNA repair by polyamines. Nat Commun. 10(1):65. |
| Hsieh IS, Gopula B, Chou CC, Wu HY, Chang GD, Wu WJ, Chang CS, Chu PC, Chen CS. Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors. (2019) J Med Chem. 62(18):8497-8510 |
| Li MY, Peng WH, Wu CH, Chang YM, Lin YL, Chang GD, Wu HC, Chen GC. (2019) PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization. Oncogene. 38(44):7002-7016. |
| Wu PY, Chuang PY, Chang GD, Chan YY, Tsai TC, Wang BJ, Lin KH, Hsu WM, Liao YF, Lee H. (2019) Novel Endogenous Ligands of Aryl Hydrocarbon Receptor Mediate Neural Development and Differentiation of Neuroblastoma. ACS Chem Neurosci.10(9):4031-4042. |
| 2018 |
Chiu YH, Yang MR, Wang LJ, Chen MH, Chang GD, Chen H. (2018) New insights into the regulation of placental growth factor gene expression by the transcription factors GCM1 and DLX3 in human placenta. J Biol Chem. 2018 Jun 22;293(25):9801-9811. |
| Yu CH, Chou CC, Tu HF, Huang WC, Ho YY, Khoo KH, Lee MS* and Chang GD*. (2018) Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase. Oncotarget, 9 (30): 21512-21529 |
| Yu CH, Chou CC, Lee DY, Khoo KH, Chang GD*. (2018) Target identification reveals protein arginine methyltransferase 1 is a potential target of phenyl vinyl sulfone and its derivatives. Biosci Rep. 38(2). pii: BSR20171717 |
| Lee DY, Huang WC, Gu TJ, Chang GD*. (2018) Quantitative and comparative liquid chromatography-electrospray ionization-mass spectrometry analyses of hydrogen sulfide and thiol metabolites derivaitized with 2-iodoacetanilide isotopologues. Journal of Chromatography A 1552, 43-52 |
| Kuo CJ, Wang ST, Lin CM, Chiu HC, Huang CR, Lee DY, Chang GD, Chou TC, Chen JW, Chen CS. (2018) A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli. Cell Death Dis. 9(3):381. |
| 2017 |
Chang CC, Chen CY, Huang CH, Wu CL, Wu HM, Chiu PF, Kor CT, Chen TH, Chang GD, Kuo CC, Wen HC, Huang CY, Chang CH. (2017) Urinary glycated uromodulin in diabetic kidney disease. Clin Sci (Lond). 131(15):1815-1829 |
| Chang CC, Chen CY, Chang GD, Chen TH, Chen WL, Wen HC, Huang CY, Chang CH. (2017) Hyperglycemia and advanced glycation end products (AGEs) suppress the differentiation of 3T3-L1 preadipocytes. Oncotarget. 8(33):55039-55050. |
| Lin TH, Hsu WH, Tsai PH, Huang YT, Lin CW, Chen KC, Tsai IH, Kandaswami CC, Huang CJ, Chang GD, Lee MT, Cheng CH. (2017) Dietary flavonoids, luteolin and quercetin, inhibit invasion of cervical cancer by reduction of UBE2S through epithelial-mesenchymal transition signaling. Food Funct. 8(4):1558-1568 |
| 2016 |
Hsu MF, Pan KT, Chang FY, Khoo KH, Urlaub H, Cheng CF, Chang GD*, Haj FG*, Meng TC*. (2016) S-Nitrosylation of Endogenous Protein Tyrosine Phosphatases in Endothelial Insulin Signaling. Free Radic Biol Med. 99, 199–213 |
| Huang WC, Lee DY, Chang GD*. (2016) Enrichment of metabolite-binding proteins by affinity elution in tandem hydrophobic interaction chromatography (AETHIC) reveals RKIP regulating ERK signaling in an ATP-dependent manner. J Proteome Res. 15, 3574-3584. |
| Tsai PH, Cheng CH, Lin CY, Huang YT, Lee LT, Kandaswami CC, Lin YC, Lee KP, Hung CC, Hwang JJ, Ke FC, Chang GD*, Lee MT*. (2016) Dietary Flavonoids Luteolin and Quercetin Suppressed Cancer Stem Cell Properties and Metastatic Potential of Isolated Prostate Cancer Cells. Anticancer Res. 36, 6367-6380. |
| Chen IT, Lee DY, Huang YT, Kou GH, Wang HC, Chang GD*, Lo CF*. (2016) Six Hours after Infection, the Metabolic Changes Induced by WSSV Neutralize the Host's Oxidative Stress Defenses. Sci Rep. 2016 6:27732. doi: 10.1038/srep27732 |
| 2015 |
Lin SJ, Lee DY, Wang HC, Kang ST, Hwang PP, Kou GH, Huang MF, Chang GD*, Lo CF*. (2015) White Spot Syndrome Virus Protein Kinase 1 (PK1) Defeats the Host Cell's Iron Withholding Defense Mechanism by Interacting with Host Ferritin. J. Virol. 89, 1083-1093 |
| Lee, DY and Chang GD* (2015), Post-staining electroblotting for reliable peptide blotting, Methods Mol. Biol. 1312:185-195 |
| Lee, DY and Chang GD* (2015), Simultaneous Immunoblotting Analysis with Activity Gel Electrophoresis and 2-D Gel Electrophoresis, Methods Mol. Biol. 1312:61-72 |
| Yu, C.H., Chou, C.C., Lee, Y.J., Khoo, K.Y., and Chang GD*. (2015) Uncovering Protein Polyamination by the Spermine-specific Antiserum and Mass Spectrometric Analysis, Amino Acids, 47, 469–481 |
| Lee, D.Y. and Chang GD* (2015), Quantitative LC-ESI-MS analysis of amine-containing metabolites derivatized with cyanuric chloride and methylamine isotopologues, J. Chromatography A, 1338, 60-68 |
| 2014 |
Su MA, Huang YT, Chen IT, Lee DY, Hsieh YC, Li CY, Ng TH, Liang SY, Lin SY, Huang SW, Chiang YA, Yu HT, Khoo KH, Chang GD, Lo CF, Wang HC. (2014) An invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathway. PLoS Pathog. 12;10(6):e1004196. |
| Lee, DY and Chang GD* (2014), Methylglyoxal in cells elicits a negative feedback loop entailing transglutaminase 2 and glyoxalase 1, Redox Biology, 2, 196-205 |
| 2012 |
Ho WH, Lee DY, Chang GD*. (2012) Proteomic Identification of a Novel Hsp90-Containing Protein-Mineral Complex Which Can Be Induced in Cells in Response to Massive Calcium Influx, J Proteome Res. 11, 3160−3174. |
| Huang JY, Liu WJ, Wang HC, Lee DY, Leu JH, Wang HC, Tsai MH, Kang ST, Chen IT, Kou GH, Chang GD*, Lo CF*. (2012) Penaeus monodon thioredoxin restores the DNA binding activity of oxidized white spot syndrome virus IE1, Antioxid Redox Signal., 17, 914-926. |
| 2011 |
Lin, F.Y., Chang, C.W., Cheong, M.L., Chen, H.C., Lee, D.Y., Chang, G.D*., Chen, H*. ( 2011 ) Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation, Nucleic Acids Res., 39(3), 848-61. |
| 2010 |
Huang, H.R., Chen, Z.J., Kunes, S., Chang, G.D., and Maniatis, T. ( 2010 ) Endocytic pathway is required for Drosophila Toll innate immune signaling, Proc. Natl. Acad. Sci. USA. 107, 8322-8327. |
| 2009 |
Lee, D.Y. and Chang G.D. ( 2009 ) Electrolytic reduction: modification of proteins occurring in isoelectric focusing electrophoresis and in electrolytic reactions in the presence of high salts, Anal. Chem., 81, 3957-3964. |
| Lee, D.Y. and Chang G.D. ( 2009 ) Simultaneous immunoblotting analysis with activity gel electrophoresis and 2-D gel electrophoresis, Methods Mol. Biol., 536, 23-33. |
| 2004 |
Tsai, P.L., Chen, C.H., Huang, C.J., Chou, C.M. and Chang, G.D. ( 2004 ) Purification and cloning of an endogenous protein inhibitor of carp nephrosin, an astacin metalloproteinase, J. Biol. Chem., 279, 11146-11155. |
| 1997 |
Hung, C. H., Huang, H. R., Huang, C. J., Huang, F. L. and Chang, G. D. ( 1997 ) Purification and cloning of carp nephrosin, a secreted zinc endopeptidase of the Astacin family, J. Biol. Chem., 272, 13772-13778. |
|